Millbury Fire received a call for a motor vehicle roll over on the mass pike ramp at route 20.
The ambulance immediately requested the availability of Lifeflight. Both drivers were pinned in their vehicles.
According to a state police press release the passenger vehicle jumped the median striking the truck in the driver's door.
One victim was pronounced deceased at the scene.
A heavy rescue truck from Auburn to assist with extrication.
The ramp was closed for a few hours while accident reconstruction mapped out the scene.