Leicester firefighters were called to the area of 500 Stafford Street for a report of an accident.
When crews arrived they found two vehicles involved in a head on crash. Both drivers were heavily entrapped in their vehicles.
Leicester firefighters called for lifeflight to respond to the scene as well as a Rescue truck from neighboring Auburn for another set of jaws.
The lifeflight helicopter was cancelled and both were transported by ground ambulance.
Firefighters worked feverishly to extricate the drivers but unfortunately one of the drivers passed as a result of their injuries.